Do you have to change the rolls between sizes or does it hold 2/3 size rolls inside and pulls the one you requested from software?

It only holds one roll. If you want to do multiples you'll need the labelwriter 450 twin turbo. It can do two rolls simultaneously.

does it print USPS priority postage

Thank you for contacting us regarding your LabelWriter 450 Turbo. It is possible to successfully print through 3rd party applications however, it is not supported by Dymo. If you experience trouble printing through USPS we would recommend contacting the 3rd party for support. If you have any questions about your LabelWriter please do not hesitate to give our technical support team a call at 877-724-8324 Monday- Friday 8am- 6pm EST as we will be happy to assist you. We appreciate your business and hope that you will continue to use Dymo products.

Thank you for contacting us regarding your LabelWriter 450. This printer can print a label with a maximum width of 2.2". The LabelWriter 4XL is the only LabelWriter than can print the 4" x 6" labels. If you have any further questions please do not hesitate to give our technical support team a call at 877-724-8324 Monday- Friday 8am- 6pm EST as we will be happy to assist you. We appreciate your business and hope that you will continue to use Dymo products.

Is this printer compatabile with a variety of different kinds of labels and sizes such as the freex wifi thermal printer?

Dymo makes many sizes and kinds of labels for use in the LabelWriter 450. You would have to ask the manufacturers/users of third party labels if their labels would work in the 450. My guess would be no, unless they are specifically made to be compatible with this printer.

Product Dimensions	5.5"D x 11.37"W x 8.37"H
Controller Type	iOS
Maximum Media Size	2 3/10"
Included Components	Dymo Label Writer 450 Twin Turbo Label Printer, Label Makers, Labels
Print media	Labels
Scanner Type	Sheetfed
Max Input Sheet Capacity	2
Compatible Devices	PC
Maximum Color Print Resolution	300 x 300 dpi
Sheet Size	2 3/10"
Maximum Black and White Print Resolution	300 dpi
Warranty Type	limited warranty
Color Depth	1 bpp
Dual-sided printing	No
Max copy resolution black-white	300 dpi
Duplex	Automatic
Hardware Interface	USB
Ink Color	No Ink
Additional Printer functions	Print Only
Control Method	App
Output sheet capacity	200
Number of Trays	2
Processor Count	1
Number of USB 2 Ports	1
Total USB Ports	1
Model Series	[INF] 450 Twin Turbo
Specific Uses For Product	personal
UPC	071701056597
Printer Ink Type	No Ink
Global Trade Identification Number	00071701056597
Memory Storage Capacity	64 MB
Manufacturer	Dymo
Item Weight	1.5 pounds
Item model number	1752266
Batteries	1 Lithium Ion batteries required.
Is Discontinued By Manufacturer	No
Material Type	Plastic/Metal
Number of Items	1
Size	1 Quarts (Pack of 1)
Manufacturer Part Number	S0838910
National Stock Number	7025-01-576-9146

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