---
product_id: 4149086
title: "Nature Made SAM-e Complete 400 mg - 60 Enteric Coated Tablets"
brand: "nature made"
price: "37496 Ft"
currency: HUF
in_stock: true
reviews_count: 6
category: "Nature Made"
url: https://www.desertcart.hu/products/4149086-nature-made-sam-e-complete-400-mg-60-enteric-coated
store_origin: HU
region: Hungary
---

# 400 mg potent dose 60-day supply, once daily Enteric coated for gentle digestion Nature Made SAM-e Complete 400 mg - 60 Enteric Coated Tablets

**Brand:** nature made
**Price:** 37496 Ft
**Availability:** ✅ In Stock

## Summary

> 💡 Elevate your mood, joints & liver health — the smart supplement for thriving pros!

## Quick Answers

- **What is this?** Nature Made SAM-e Complete 400 mg - 60 Enteric Coated Tablets by nature made
- **How much does it cost?** 37496 Ft with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.hu](https://www.desertcart.hu/products/4149086-nature-made-sam-e-complete-400-mg-60-enteric-coated)

## Best For

- nature made enthusiasts

## Why This Product

- Trusted nature made brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Mood Mastery:** Boosts neurotransmitters dopamine & serotonin for balanced mental wellness
- • **Joint Guardian:** Supports cartilage health to keep you moving with ease
- • **Daily Simplicity:** One tablet a day keeps the blues and joint aches away
- • **Clinically Trusted:** Backed by thousands of 4.5-star reviews and decades of use
- • **Liver Detox Dynamo:** Enhances natural liver detoxification and overall function

## Overview

Nature Made SAM-e Complete delivers a clinically effective 400 mg dose in enteric coated tablets designed for optimal absorption and gentle digestion. This supplement supports balanced neurotransmitter levels to enhance mood, promotes joint cartilage maintenance, and aids liver detoxification. With a convenient once-daily regimen and strong user satisfaction, it’s a trusted choice for professionals seeking holistic mental and physical wellness.

## Description

Nature Made's newest 400 mg 60 tablets production. One Tablet per day. Nature Made SAM-e Complete enhances mood by promoting a healthy balance of neurotransmitters, dopamine and serotonin, which are part of overall healthy brain cell functions. Promotes joint health by helping to maintain joint cartilage which naturally deteriorates with physical activity and age. Helps support detoxification and overall healthy liver functions.

Review: Life Saver - I purchased this product for my teenaged son, who has suffered from depression on and off over the last few years. I know people who take medication such as Prozac for depression and I don't like the way it effects them. I certainly didn't want that for my son, yet it was getting very difficult to watch him suffer. I knew something needed to change. I had tried St. John's Wort but that did nothing for him. After extensive research, I decided to try Sam-e as a last ditch effort before making an appointment to try Rx meds. He started with one 400 mg pill in the morning, but after 10 days, there was no change. We then tried two 400 mg pills in the morning as well as a B Complex vitamin. That was the difference maker. Within the first few days, he started to feel better. It was like a dark cloud lifting. A week after the new dose, he was a different kid - lighter mood, happier disposition, and more positive than negative. It's been close to a month now and the results are wonderful. I can't believe the difference. I haven't heard him make a negative comment in weeks. He says he feels happier. He is enjoying life and doesn't get so overwhelmed with the little things. High school is tough on any teenager, but he seems to be handling things much better now. We have not encountered any stomach issues at all. He takes his pills first thing in the morning and then has breakfast about 30-40 minutes later. I'm so grateful for this product. It has been a lifesaver. I just hope the effects last. My advice to anyone who is looking for an alternative to prescription medication to try this. Don't give up if the first dose doesn't work. You can always increase it. My son's dose of 800 mg is only half of what is recommended, so there is plenty of room to increase if it would ever become necessary. The B Complex vitamin is a great complement to Sam-e, as B vitamins are apparently needed for the Sam-e to absorb better.
Review: It is better for me than the Rx drugs ever were. - I am 60 years old. I had been on anti-depressants since 1989 when I was faced with the loss of my job, husband, car and home in a divorce. I began supplementing with anti-anxity drugs last year, 2012, when I had a complete nervous breakdown due to new issues that I was facing. In April of this year, it had been almost a calendar year since this breakdown and I was still not feeling any better. Before Sam-e, on every given day since April 2012, I simply could not concieve of spending the rest of my life feeling like I did. I slept until noon just to avoid getting up. My husband did not know what to do to help me. I cried disparingly almost all of the time and would not leave the house. Finally, in April 2013, I decided to go visit my Mom and we happened into a thrift store where I picked up a book written by a man praising Sam-e. I realized then that I had everything to loose and everything to gain. So I purchased Sam-e 400 mg and bless the day I did. I can tell you that within days (2-3) I was feeling better. It has now been 6 weeks since I discontinued any Rx drugs for depression and/or anxiety; taking only the Sam-e. I feel that this is truely remarkable since the Rx drugs were not making me feel better and I was only getting worse before taking Sam-e. I can tell you I now am a changed person; I am now the person I was before this world and politics took its toll on me. I can do this now and have renewed optimism, energy and a sense of well-being that I did not have before. To date, I have experienced no side effects and will continue taking Sam-e 400mg once a day. I will update you if there is a change of any kind.

## Features

- Aids in enhancing your mood.
- Promotes joint health.
- Helps support detoxification and overall healthy liver functions.
- Support normal mental health.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B00655Z37Y |
| Best Sellers Rank | #32,284 in Health & Household ( See Top 100 in Health & Household ) #137 in CoQ10 Nutritional Supplements |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,445) |
| Date First Available  | February 19, 2011 |
| Is Discontinued By Manufacturer  | No |
| Item model number  | 2N590598C |
| Manufacturer  | Nature Made® |
| Product Dimensions  | 7 x 3.37 x 8.25 inches; 4.23 ounces |

## Product Details

- **Brand:** Nature Made
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Item Weight:** 0.12 Kilograms
- **Item dimensions L x W x H:** 7 x 3.37 x 8.25 inches
- **Primary Supplement Type:** SAM-e
- **Product Benefits:** Mood Support,Joint Support
- **Special Ingredients:** Joint Support, Mood Support
- **Unit Count:** 60 Count

## Images

![Nature Made SAM-e Complete 400 mg - 60 Enteric Coated Tablets - Image 1](https://m.media-amazon.com/images/I/61868xEGaqL.jpg)

## Questions & Answers

**Q: Does this have milk thistle in it?**
A: Nature Made lists the ingredients on the box. All are scientific/chemical names; "milk thistle" is a common name.  I'd suggest that you ask your doctor or pharmacist to interpret these ingredients for you.

**Q: are pills individually wrapped?**
A: They are in a foil pack...so yes, they are individually wrapped.

**Q: Where is this product manufactured(what country)?  Neither box nor website says.**
A: The website said most of Nature Made products are manufactured in Southern CA.  A few are located overseas, but not in China.I have been taking Sam-e for about six or seven years and it works.

**Q: Why does the origin say albania?**
A: Honestly I never noticed that. I just know the product works well for me when I start feeling down, and that is what matters to me.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Life Saver
*by S***L on February 9, 2016*

I purchased this product for my teenaged son, who has suffered from depression on and off over the last few years. I know people who take medication such as Prozac for depression and I don't like the way it effects them. I certainly didn't want that for my son, yet it was getting very difficult to watch him suffer. I knew something needed to change. I had tried St. John's Wort but that did nothing for him. After extensive research, I decided to try Sam-e as a last ditch effort before making an appointment to try Rx meds. He started with one 400 mg pill in the morning, but after 10 days, there was no change. We then tried two 400 mg pills in the morning as well as a B Complex vitamin. That was the difference maker. Within the first few days, he started to feel better. It was like a dark cloud lifting. A week after the new dose, he was a different kid - lighter mood, happier disposition, and more positive than negative. It's been close to a month now and the results are wonderful. I can't believe the difference. I haven't heard him make a negative comment in weeks. He says he feels happier. He is enjoying life and doesn't get so overwhelmed with the little things. High school is tough on any teenager, but he seems to be handling things much better now. We have not encountered any stomach issues at all. He takes his pills first thing in the morning and then has breakfast about 30-40 minutes later. I'm so grateful for this product. It has been a lifesaver. I just hope the effects last. My advice to anyone who is looking for an alternative to prescription medication to try this. Don't give up if the first dose doesn't work. You can always increase it. My son's dose of 800 mg is only half of what is recommended, so there is plenty of room to increase if it would ever become necessary. The B Complex vitamin is a great complement to Sam-e, as B vitamins are apparently needed for the Sam-e to absorb better.

### ⭐⭐⭐⭐⭐ It is better for me than the Rx drugs ever were.
*by D***N on July 4, 2013*

I am 60 years old. I had been on anti-depressants since 1989 when I was faced with the loss of my job, husband, car and home in a divorce. I began supplementing with anti-anxity drugs last year, 2012, when I had a complete nervous breakdown due to new issues that I was facing. In April of this year, it had been almost a calendar year since this breakdown and I was still not feeling any better. Before Sam-e, on every given day since April 2012, I simply could not concieve of spending the rest of my life feeling like I did. I slept until noon just to avoid getting up. My husband did not know what to do to help me. I cried disparingly almost all of the time and would not leave the house. Finally, in April 2013, I decided to go visit my Mom and we happened into a thrift store where I picked up a book written by a man praising Sam-e. I realized then that I had everything to loose and everything to gain. So I purchased Sam-e 400 mg and bless the day I did. I can tell you that within days (2-3) I was feeling better. It has now been 6 weeks since I discontinued any Rx drugs for depression and/or anxiety; taking only the Sam-e. I feel that this is truely remarkable since the Rx drugs were not making me feel better and I was only getting worse before taking Sam-e. I can tell you I now am a changed person; I am now the person I was before this world and politics took its toll on me. I can do this now and have renewed optimism, energy and a sense of well-being that I did not have before. To date, I have experienced no side effects and will continue taking Sam-e 400mg once a day. I will update you if there is a change of any kind.

### ⭐⭐⭐⭐⭐ Works great
*by T***. on August 20, 2025*

Good product

## Frequently Bought Together

- Nature Made SAM-e Complete 400 mg - 60 Enteric Coated Tablets
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- Nature's Made Sam-e Complete 400-mg 36 Tablets (2 Pack)

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*Product available on Desertcart Hungary*
*Store origin: HU*
*Last updated: 2026-02-24*