The Cell Cycle: Principles of Control (Primers in Biology) (Primers in Biology) 1st Edition

The Cell Cycle is one of those books which sat on my desk for three months after a brief look. Then I had to look up something and went back to it and found that I could not put it down. It is a superbly well done book which combines simplicity of presentation with detail and completeness. It may not be the easiest to learn from as a first book, but not bad, but it is a wonderful addition to any library for ready reference and recall. It also contains on a page by page basis the key source reference for most of the experimental efforts leading to the related presentation.It starts out with a reasonable overview as well as a discussion of certain mammal cell cycles. Then in Chapter 3 it does a superb job of setting up the cyclin dependent kinases and related cell control system elements. On p 43 the authors commence an exceptionally clear and useful presentation of the dynamics of the cell cycle in the context or reaction dynamics. Although this lacks the mathematical detail of the text by Klipp et al  Systems Biology: A Textbook  it does provide a fantastic reference to see how the cyclins and other elements react in the dynamics of the overall cell cycle. This modeling is very useful for modeling cancer in a systems context when combined with other pathway elements. Pages 51 and 55 are well done presentations of the dynamics of these cycles including the key elements of cell cycle control.Chapters 4 through 9 detail each of the steps in the cell cycle. Then in Chapter 10 the authors provide an exceptionally lucid explanation of cell proliferation. Again this is quite useful in cancer system modeling. Pages 207, 210 and 211 graphically show various useful examples of cell proliferation mechanisms. I would have liked to see a more complete discussion of what initiates cell cycles but they detail in the work is adequate.Chapter 12 is a well done presentation of cancer viewed from the perspective of the cell cycle. This is a reasonably complete presentation and is short enough that the focus on the cell cycle portion comes to the fore. I would have liked to see some discussion of the cancer stem cell issue but it is still somewhat premature in the context of the cell cycle.Overall this is one of the four or five key reference books that can be used on an almost daily basis. It helps fill in gaps from time to time and is a well needed gap between Weinberg  The Biology of Cancer  and Klipp. I would strongly recommend it for any working library. The new insights initiated from each page are well worth it.

This is the best book about cell cycle you can read.The author wrote in the preface citing the architect Le Corbusier: "There are no details.Everything is an essential part of a whole.In nature microcosm and macrocosm are one"This is the philosophy behind this book...you will find every detail as part of the big picture.Very good and helpful illustrations and diagrams help the reader to understand concepts and pathways.

This book is awesome! It provides a great foundation for understanding more detailed papers in the literature. It has very quickly filled a lot of gaps in my knowledge. I finally feel like I have a good conceptual understanding of the cell cycle. Thanks to the authors for taking the time to do this right.

This book describes the regular cycles of a cell. It is not meant for lay people, but as a non-bio major, I was able to read through the whole thing, and make a coherent presentation on the cell cycle in great detail.

Excellent book!Great for an undergrad or grad student, but most importantly, it is the perfect resource for every cell biologist at all levels. A great starting point for the various cell cycle model organisms without sifting through piles of outdated or wrong reviews.This is one of the more handy books that sits on my shelf.

Best cell cycle book ever!

In my view the most comprehensive textbook about cell cycle regulation in every relevant model organism. Four stars because it is a bit outdated (2006 edition). Yet, most of the principles still apply.

Gutes Buch, unser Prof hatte die Vorlesung darauf aufgebaut. Es ist sehr verständlich geschrieben und für ein Fachbuch sehr gut zu lesen, alles recht gut erklärt und viel mit Grafiken untermalt. Auch die Gliederung war sehr logisch, die Themenbereiche sind meist auf einer (manchmal 2) Doppelseiten erklärt. Auch gut fand ich die Definitionen am Ende einer Seite, wenn neue Begriffe eingeführt wurden.